Map of resistance to carbapenems in Pseudomonas aeruginosa in the world

September 23, 2023

Resistance to carbapenems in Pseudomonas aeruginosa This is a growing global health problem. Resistance levels vary widely around the world. Latest publication focuses on understanding the prevalence and spread of this resistance in different countries.

In most countries, the prevalence ranges between 10% and 50%. For example, countries like Canada and the Dominican Republic have low rates, around 3.3% and 8% respectively. Meanwhile, Australia, North America and several European countries have figures of 10% to 30%. On the contrary, such countries Brazil, Peru, Costa Rica, Russia, Greece, Poland, Iran And Saudi Arabia This figure is higher than 50%, indicating real concern for public health.

Resistance to carbapenems in P. aeruginosa This is related to the presence of carbapenemase. According to a 2018 Centers for Disease Control and Prevention report, 1.9% of viruses were isolated P. aeruginosa resistant to carbapenems are carbapenemase producers. The distribution of these enzymes varies throughout the world, especially metallo-β-lactamases VIM groupbeing the most dominant, followed by IMP And NDM. Other carbapenemases have a more regional distribution, e.g SPM in Brazil, Switzerland, England, China and India, DIM in Poland, GIMP in Germany, driver’s license In China, HMB in Germany and America, camera In Canada, OBJECTIVE in Australia and FIM in Italy. Clone of P. aeruginosa manufacturer of KPC And GES in Europe and Asia, while carbapenemases of the type OK This disease has been least identified and reported in Spain, India, England and Belgium.

The heat map shows the global distribution of Pseudomonas aeruginosa carbapenemase, with colored areas corresponding to geographic regions with predominance of certain carbapenemase groups. a): KPC; (b): GES carbapenemase; (c): PMI; (d): VIM; (e): NDM. Heat maps were extracted using Antimicrobial Testing, Leadership and Surveillance (ATLAS) data. Can be accessed via: https://atlas-surveillance.com.

Resistance to carbapenems in P. aeruginosa This is an increasing challenge for public health throughout the world. Understanding the prevalence and distribution of carbapenemases is critical to effectively address this problem. Continued surveillance efforts and international collaboration are needed to combat the spread of this resistance and maintain the effectiveness of this important antibiotic.

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Stuart Martin

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